Macrophage scavenger receptor a promotes tumor progression in murine models of ovarian and pancreatic cancer.

Alternatively activated macrophages express the pattern recognition receptor scavenger receptor A (SR-A). We demonstrated previously that coculture of macrophages with tumor cells upregulates macrophage SR-A expression. We show in this study that macrophage SR-A deficiency inhibits tumor cell migrat...

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Bibliographic Details
Main Authors: Neyen, C, Plüddemann, A, Mukhopadhyay, S, Maniati, E, Bossard, M, Gordon, S, Hagemann, T
Format: Journal article
Language:English
Published: 2013