Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants

Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants

The reconciliation between Mendelian inheritance of discrete traits and the genetically based correlation between relatives for quantitative traits was Fisher's infinitesimal model of a large number of genetic variants, each with very small effects, whose causal effects could not be individuall...

書誌詳細
主要な著者:	Crouch, DJM, Bodmer, WF
フォーマット:	Journal article
言語:	English
出版事項:	National Academy of Sciences 2020

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