Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants

Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants

The reconciliation between Mendelian inheritance of discrete traits and the genetically based correlation between relatives for quantitative traits was Fisher's infinitesimal model of a large number of genetic variants, each with very small effects, whose causal effects could not be individuall...

書目詳細資料
Main Authors:	Crouch, DJM, Bodmer, WF
格式:	Journal article
語言:	English
出版:	National Academy of Sciences 2020

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