Th cells act via two synergistic pathways to promote antiviral CD8+ T cell responses.

The mechanisms of how Th cells promote CD8(+) T cell responses during viral infections are largely unknown. In this study, we unraveled the mechanisms of T cell help for CD8(+) T cell responses during vaccinia virus infection. Our results demonstrate that Th cells promote vaccinia virus-specific CD8...

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Bibliographic Details
Main Authors: Wiesel, M, Joller, N, Ehlert, A, Crouse, J, Spörri, R, Bachmann, M, Oxenius, A
Format: Journal article
Language:English
Published: 2010