Identification of a cryptic bacterial promoter in mouse (mdr1a) P-glycoprotein cDNA

The efflux transporter P-glycoprotein (P-gp) is an important mediator of various pharmacokinetic parameters, being expressed at numerous physiological barriers and also in multidrug-resistant cancer cells. Molecular cloning of homologous cDNAs is an important tool for the characterization of functio...

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Main Authors: Pluchino, KM, Esposito, D, Moen, JK, Hall, MD, Madigan, JP, Shukla, S, Procter, LV, Wall, VE, Schneider, TD, Pringle, I, Ambudkar, SV, Gill, D, Hyde, SC, Gottesman, MM
Format: Journal article
Language:English
Published: Public Library of Science 2015