HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function.

The use of peptide-human histocompatibility leukocyte antigen (HLA) class I tetrameric complexes to identify antigen-specific CD8(+) T cells has provided a major development in our understanding of their role in controlling viral infections. However, questions remain about the exact function of thes...

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Bibliographic Details
Main Authors:	Appay, V, Nixon, D, Donahoe, S, Gillespie, G, Dong, T, King, A, Ogg, G, Spiegel, H, Conlon, C, Spina, C, Havlir, D, Richman, D, Waters, A, Easterbrook, P, Mcmichael, A, Rowland-Jones, S
Format:	Journal article
Language:	English
Published:	2000

HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function.

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