ANTI-CD3 therapy expands the numbers of CD4+ and CD8+ Treg cells and induces sustained amelioration of collagen-induced arthritis.
OBJECTIVE: To assess the therapeutic potential of anti-CD3 monoclonal antibodies (mAb) for rheumatoid arthritis, using collagen-induced arthritis as an animal model. METHODS: Arthritis was induced in DBA/1 mice by immunization with type II collagen. After disease onset, a single injection of anti-C...
প্রধান লেখক: | Notley, C, McCann, F, Inglis, J, Williams, R |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2010
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অনুরূপ উপাদানগুলি
অনুরূপ উপাদানগুলি
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