A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer

A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer

Genetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.536 T > C; Ile163Thr-substitution in PSA) is associated with reduced prostate cancer risk, however, the functional relevance...

Full description

Bibliographic Details
Main Authors:	Srinivasan, S, Kryza, T, Bock, N, Tse, BWC, Sokolowski, KA, Janaththani, P, Fernando, A, Moya, L, Stephens, C, Dong, Y, Röhl, J, Alinezhad, S, Vela, I, Perry-Keene, JL, Buzacott, K, Nica, R, Gago-Dominguez, M, Schleutker, J, Maier, C, Muir, K, Tangen, CM, Gronberg, H, Pashayan, N, Albanes, D, Travis, RC, Neal, DE
Format:	Journal article
Language:	English
Published:	Nature Research 2024

Similar Items

A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer
by: Srilakshmi Srinivasan, et al.
Published: (2024-11-01)

Cluster effect for SNP–SNP interaction pairs for predicting complex traits
by: Lin, H, et al.
Published: (2024)

Cluster effect for SNP–SNP interaction pairs for predicting complex traits
by: Hui-Yi Lin, et al.
Published: (2024-08-01)

KLK3 SNP–SNP interactions for prediction of prostate cancer aggressiveness
by: Hui-Yi Lin, et al.
Published: (2021-04-01)

PSA is dead, long live PSA.
by: Vickers, A, et al.
Published: (2012)

Blood levels of free-PSA but not complex-PSA significantly correlates to prostate release of PSA in semen in young men, while blood levels of complex-PSA, but not free-PSA increase with age.
by: Sävblom, C, et al.
Published: (2005)

Serbest PSA/Total pSA Oranının Günlük Varyasyonu
by: Fatma Özdemir, et al.
Published: (2011-06-01)

Total PSA and free PSA in patients with severe liver dysfunction
by: Rama Devi Mittal, et al.
Published: (2003-01-01)

Relation between Serum Level of Total PSA and Free PSA/Total PSA Ratio with Grade of Prostate Cancer
by: Mohammad Yazdani, et al.
Published: (2013-10-01)

Association of Obesity and Smoking With PSA and PSA Velocity in Men With Prostate Cancer
by: Amit M. Algotar PhD, MBBS, et al.
Published: (2011-05-01)

Comparison between PSA density, free PSA percentage and PSA density in the transition zone in the detection of prostate cancer in patients with serum PSA between 4 and 10 ng/ml
by: Emerson P. Gregorio, et al.
Published: (2007-04-01)

Controversies in PSA screening
by: O'Sullivan, J
Published: (2017)

When is an SNP not an SNP?
by: Shapour Jalilzadeh, et al.
Published: (2024-09-01)

Association between polymorphisms in the prostate-specific antigen (PSA) promoter and release of PSA.
by: Sävblom, C, et al.
Published: (2009)

Genetic correction of PSA values using sequence variants associated with PSA levels.
by: Gudmundsson, J, et al.
Published: (2010)

CUT-OFF POINT OF PSA AND PSA DENSITY IN PROSTATE CANCER SUSPECTED PATIENTS
by: Daniel Simanjuntak, et al.
Published: (2016-03-01)

Zonal adjusted PSA density improves prostate cancer detection rates compared with PSA in Taiwanese males with PSA < 20 ng/ml
by: Tsung-Hsin Chang, et al.
Published: (2020-10-01)

Quality assessment for prostate-specific antigen (PSA) in relation to ERSPC: report of the PSA committee.
by: Blijenberg, BG, et al.
Published: (2003)

Utility of PSA isoform-[-2] proPSA (p2PSA) and prostate health index in the diagnosis of prostate cancer: A study in Indian population
by: Govinda Raju NL, et al.
Published: (2022-01-01)

Printonix PSA : P5215 /
by: Universiti Teknologi Malaysia Perpustakaan 3383, et al.
Published: (2000)

PSA Kuasai Sirkit enam
by: Harian Metro,
Published: (2012)

2023 PSA ANNUAL MEETING
Published: (2023-12-01)

PSA screening - for whom and when?
by: Peter Albers
Published: (2019-01-01)

Assessment of the many faces of PsA: single and composite measures in PsA clinical trials
by: McGagh, D, et al.
Published: (2020)

Age-specific reference intervals for Prostate-Specific-Antigen (PSA), its isoform-[-2] pro-PSA (p2PSA) and prostate health index in Indian males
by: Govinda Raju NL, et al.
Published: (2024-04-01)

Free PSA performs better than total PSA in predicting prostate volume in Chinese men with PSA levels of 2.5–9.9 ng ml−1
by: Ma-Ping Huang, et al.
Published: (2023-01-01)

Variation in percentage-free prostate-specific antigen (PSA) with prostate volume, age and total PSA level.
by: Törnblom, M, et al.
Published: (2001)

Kajian 'H PSA-RMN (PSA-RMN) terhadap struktur sistem kaca binari stanas fosfat /
by: Shaharudin Ali, et al.
Published: (2001)

Predictors of Clinically Significant Prostate Cancer: A Comparative Study of PSA, PSA Density, and MRI Parameters
by: Mehmet Coşkun, et al.
Published: (2021-02-01)

Correlación entre valores del PSA total y PSA libre con cáncer de próstata
by: Xavier Delgado C., et al.
Published: (2022-09-01)

Correlación entre valores del PSA total y PSA libre con cáncer de próstata
by: Xavier Delgado C.
Published: (2022-09-01)

AGE, TOTAL PSA, PSA DENSITY AND GLEASON SCORE, TAUS AS PREDICTIVE FACTORS IN PATIENTS WITH PROSTATE CANCER
by: Daruqutni Albar, et al.
Published: (2016-03-01)

Free PSA estimation substituted by calculation where total PSA value is up to 4 ng/ml
by: M Dhumne, et al.
Published: (2006-01-01)

SNP-VISTA: An interactive SNP visualization tool
by: Hugenholtz Philip, et al.
Published: (2005-12-01)

SNP-SNP interactions in breast cancer susceptibility
by: Wang Yuanyuan, et al.
Published: (2006-05-01)

On Optimizing PSA Berth Planning System
by: Teo, Chung Piaw, et al.
Published: (2003)

PSA campaign outline / Norsharina Samsuri
by: Samsuri, Norsharina
Published: (2014)

Design and simulation of the PSA truck with trailer
by: Tian, Shuo.
Published: (2011)

Fasting times in serum PSA assay
by: Xiang Xu, et al.
Published: (2014-10-01)

Experimental Verification of the Modified PSA Algorithm
by: Xiao Li, et al.
Published: (2022-01-01)