A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer

A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer

Genetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.536 T > C; Ile163Thr-substitution in PSA) is associated with reduced prostate cancer risk, however, the functional relevance...

書誌詳細
主要な著者:	Srinivasan, S, Kryza, T, Bock, N, Tse, BWC, Sokolowski, KA, Janaththani, P, Fernando, A, Moya, L, Stephens, C, Dong, Y, Röhl, J, Alinezhad, S, Vela, I, Perry-Keene, JL, Buzacott, K, Nica, R, Gago-Dominguez, M, Schleutker, J, Maier, C, Muir, K, Tangen, CM, Gronberg, H, Pashayan, N, Albanes, D, Travis, RC, Neal, DE
フォーマット:	Journal article
言語:	English
出版事項:	Nature Research 2024

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