IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) is a life-threatening pathogen in humans. Bacterial infection of macrophages usually triggers strong innate immune mechanisms, including IL-1 cytokine secretion. The newer member of the IL-1 family, IL-36, was recently shown to be involved in cellular defense against...

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Bibliographic Details
Main Authors: Ahsan, F, Maertzdorf, J, Guhlich-Bornhof, U, Kaufmann, S, Moura-Alves, P
Format: Journal article
Language:English
Published: Springer Nature 2018