IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) is a life-threatening pathogen in humans. Bacterial infection of macrophages usually triggers strong innate immune mechanisms, including IL-1 cytokine secretion. The newer member of the IL-1 family, IL-36, was recently shown to be involved in cellular defense against...
Main Authors: | Ahsan, F, Maertzdorf, J, Guhlich-Bornhof, U, Kaufmann, S, Moura-Alves, P |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2018
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