IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) is a life-threatening pathogen in humans. Bacterial infection of macrophages usually triggers strong innate immune mechanisms, including IL-1 cytokine secretion. The newer member of the IL-1 family, IL-36, was recently shown to be involved in cellular defense against...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ahsan, F, Maertzdorf, J, Guhlich-Bornhof, U, Kaufmann, S, Moura-Alves, P
التنسيق: Journal article
اللغة:English
منشور في: Springer Nature 2018