Pancreatic β-cell electrical activity and insulin secretion: of mice and men

The pancreatic β-cell plays a key role in glucose homeostasis by secreting insulin, the only hormone capable of lowering the blood glucose concentration. Impaired insulin secretion results in the chronic hyperglycemia that characterizes type 2 diabetes (T2DM), which currently afflicts >450 mi...

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Bibliographic Details
Main Authors: Rorsman, P, Ashcroft, F
Format: Journal article
Language:English
Published: American Physiological Society 2017