Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion

To maintain prolonged infection of mammals, African trypanosomes have evolved remarkable surface coats and a system of antigenic variation1. Within these coats are receptors for macromolecular nutrients such as transferrin2,3. These must be accessible to their ligands but must not confer susceptibil...

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Bibliographic Details
Main Authors: Trevor, C, Gonzalez-Munoz, A, Macleod, O, Woodcock, P, Rust, S, Vaughan, T, Garman, E, Minter, R, Carrington, M, Higgins, M
Format: Journal article
Language:English
Published: Springer Nature 2019