Horizontally acquired AT-rich genes in Escherichia coli cause toxicity by sequestering RNA polymerase

Horizontal gene transfer permits rapid dissemination of genetic elements between individuals in bacterial populations. Transmitted DNA sequences may encode favourable traits. However, if the acquired DNA has an atypical base composition, it can reduce host fitness. Consequently, bacteria have evolve...

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Bibliographic Details
Main Authors: Lamberte, L, Baniulyte, G, Singh, S, Stringer, A, Bonocora, R, Stracy, M, Kapanidis, A, Wade, J, Grainger, D
Format: Journal article
Language:English
Published: Springer Nature 2017