A protocol for simultaneous high-sensitivity genotyping and chromatin accessibility profiling in single cells.

<p>Single-cell assay for transposase-accessible chromatin with sequencing (scATAC-seq) resolves the heterogeneity of epigenetic states across cells but does not typically capture exonic mutations, which limits our knowledge of how somatic mutations alter chromatin landscapes. Here, we present...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Turkalj, S, Jakobsen, NA, Groom, A, Radtke, FA, Vyas, P
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Cell Press 2023