Molecular imaging with optical coherence tomography using ligand-conjugated microparticles that detect activated endothelial cells: rational design through target quantification.

OBJECTIVES: Optical coherence tomography (OCT) is a high resolution imaging technique used to assess superficial atherosclerotic plaque morphology. Utility of OCT may be enhanced by contrast agents targeting molecular mediators of inflammation. METHODS AND RESULTS: Microparticles of iron oxide (MPIO...

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Bibliographic Details
Main Authors: Jefferson, A, Wijesurendra, R, McAteer, M, Digby, J, Douglas, G, Bannister, T, Perez-Balderas, F, Bagi, Z, Lindsay, A, Choudhury, R
Format: Journal article
Language:English
Published: 2011