Evolutionary relationships and protein domain architecture in an expanded calpain superfamily in kinetoplastid parasites.

Employing whole-genome analysis we have characterized a large family of genes coding for calpain-related proteins in three kinetoplastid parasites. We have defined a total of 18 calpain-like sequences in Trypanosoma brucei, 27 in Leishmania major, and 24 in Trypanosoma cruzi. Sequence characterizati...

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Bibliographic Details
Main Authors: Ersfeld, K, Barraclough, H, Gull, K
Format: Journal article
Language:English
Published: 2005