Mutational analysis of isoform selectivity and conformational equilibria in protein kinase inhibition
<p>Deregulation of protein kinases is associated with many diseases making them important targets for therapeutic intervention. Kinases can switch between active and inactive conformations that can be targeted by type 1 or type 2 inhibitors respectively. One of the most relevant conformational...
| Autor principal: | |
|---|---|
| Otros Autores: | |
| Formato: | Tesis |
| Lenguaje: | English |
| Publicado: |
2015
|
| Materias: |