Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing.
microRNAs (miRNAs) silence gene expression by suppressing protein production and/or by promoting mRNA decay. To elucidate how silencing is accomplished, we screened an RNA interference library for suppressors of miRNA-mediated regulation in Drosophila melanogaster cells. In addition to proteins know...
Hauptverfasser: | Eulalio, A, Rehwinkel, J, Stricker, M, Huntzinger, E, Yang, S, Doerks, T, Dorner, S, Bork, P, Boutros, M, Izaurralde, E |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2007
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