Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes

Body fat distribution is a major, heritable risk factor for cardiometabolic disease, independent of overall adiposity. Using exome-sequencing in 618,375 individuals (including 160,058 non-Europeans) from the UK, Sweden and Mexico, we identify 16 genes associated with fat distribution at exome-wide s...

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Bibliographic Details
Main Authors: Akbari, P, Sosina, OA, Bovijn, J, Torres, J, Emberson, J, Collins, R, Rader, D
Format: Journal article
Language:English
Published: Springer Nature 2022