Multiple Ets factors and interferon regulatory factor-4 modulate CD68 expression in a cell type-specific manner.

CD68 is a transmembrane glycoprotein expressed in all cells of the mononuclear phagocyte lineage including monocytes and tissue resident macrophages. Deletion analysis of the 5'-flanking sequences of the gene demonstrated that the proximal -150-bp sequence of the CD68 promoter exhibits high lev...

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Autori principali: O'Reilly, D, Quinn, C, El-Shanawany, T, Gordon, S, Greaves, D
Natura: Journal article
Lingua:English
Pubblicazione: 2003