The spinal muscular atrophy protein SMN affects Drosophila germline nuclear organization through the U body-P body pathway.

The spinal muscular atrophy protein SMN affects Drosophila germline nuclear organization through the U body-P body pathway.

Survival motor neuron protein (SMN) is the determining factor for the human neurodegenerative disease spinal muscular atrophy (SMA). SMN is critical for small nuclear ribonucleoprotein (snRNP) assembly. Using Drosophila oogenesis as a model system, we show that mutations in smn cause abnormal nuclea...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Lee, L, Davies, SE, Liu, J
التنسيق: Journal article
اللغة:English
منشور في: 2009

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