An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia.

BACKGROUND: The artemisinin-based combination treatment (ACT) of dihydroartemisinin (DHA) and piperaquine (PQP) is a promising novel anti-malarial drug effective against multi-drug resistant falciparum malaria. The aim of this study was to show non-inferiority of DHA/PQP vs. artesunate-mefloquine (...

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Bibliographic Details
Main Authors: Valecha, N, Phyo, A, Mayxay, M, Newton, P, Krudsood, S, Keomany, S, Khanthavong, M, Pongvongsa, T, Ruangveerayuth, R, Uthaisil, C, Ubben, D, Duparc, S, Bacchieri, A, Corsi, M, Rao, B, Bhattacharya, P, Dubhashi, N, Ghosh, S, Dev, V, Kumar, A, Pukrittayakamee, S, Pukittayakamee, S
Format: Journal article
Language:English
Published: Public Library of Science 2010