The bisphosphonate-ester apornine does not act by inhibiting protein prenylation, but enhances the effects of lovastatin on myeloma cells

Documenti analoghi

• Apomine, an inhibitor of HMG-COA-reductase, does not act by inhibiting protein prenylation in human myeloma cells in vitro
  di: Roelofs, A, et al.
  Pubblicazione: (2005)
• Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells.
  di: Roelofs, A, et al.
  Pubblicazione: (2006)
• Risedronate, and its phosphonocarboxylate analogue NE10790, both induce apoptosis, but have differential effects on the cell cycle and protein prenylation in human myeloma cells.
  di: Roelofs, A, et al.
  Pubblicazione: (2004)
• Nitrogen-containing bisphosphonates induce apoptosis in human bone marrow-derived myeloma cells in vitro by inhibiting protein prenylation.
  di: Gordon, S, et al.
  Pubblicazione: (1999)
• Studies to elucidate the anti-tumor mechanism of action of risedronate in human myeloma cells; Use of an analogue of risedronate reveals the effects of differential inhibition of prenylation
  di: Roelofs, A, et al.
  Pubblicazione: (2005)