Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria.

BACKGROUND: Our study examined the relative contributions of host, pharmacokinetic, and parasitological factors in determining the therapeutic response to artemether-lumefantrine (AL). METHODS: On the northwest border of Thailand, patients with uncomplicated Plasmodium falciparum malaria were enroll...

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Bibliographic Details
Main Authors: Price, R, Uhlemann, A, van Vugt, M, Brockman, A, Hutagalung, R, Nair, S, Nash, D, Singhasivanon, P, Anderson, T, Krishna, S, White, N, Nosten, F
Format: Journal article
Language:English
Published: 2006