Tumor imaging using radiolabelled matrix metalloproteinase-activated anthrax proteins
<p><strong>Purpose:</strong> Increased activity of matrix metalloproteinases (MMPs) is associated with worse prognosis in different cancer types. The protective antigen (PA-WT) of the binary anthrax lethal toxin was modified to form a pore in cell membranes only when cleaved by MMP...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Journal article |
Published: |
Society of Nuclear Medicine and Molecular Imaging
2019
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