Tumor imaging using radiolabelled matrix metalloproteinase-activated anthrax proteins
<p><strong>Purpose:</strong> Increased activity of matrix metalloproteinases (MMPs) is associated with worse prognosis in different cancer types. The protective antigen (PA-WT) of the binary anthrax lethal toxin was modified to form a pore in cell membranes only when cleaved by MMP...
Hlavní autoři: | Xavier, M, Liu, S, Bugge, T, Baguna-Torres, J, Mosley, M, Hopkins, S, Allen, P, Berridge, G, Vendrell, I, Fischer, R, Kersemans, V, Smart, S, Leppla, S, Cornelissen, B |
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Médium: | Journal article |
Vydáno: |
Society of Nuclear Medicine and Molecular Imaging
2019
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