Tumor imaging using radiolabelled matrix metalloproteinase-activated anthrax proteins
<p><strong>Purpose:</strong> Increased activity of matrix metalloproteinases (MMPs) is associated with worse prognosis in different cancer types. The protective antigen (PA-WT) of the binary anthrax lethal toxin was modified to form a pore in cell membranes only when cleaved by MMP...
Main Authors: | Xavier, M, Liu, S, Bugge, T, Baguna-Torres, J, Mosley, M, Hopkins, S, Allen, P, Berridge, G, Vendrell, I, Fischer, R, Kersemans, V, Smart, S, Leppla, S, Cornelissen, B |
---|---|
格式: | Journal article |
出版: |
Society of Nuclear Medicine and Molecular Imaging
2019
|
相似書籍
-
[18F]Olaparib: Precision radiolabelling of PARP inhibitors for in vivo imaging
由: Wilson, T, et al.
出版: (2018) -
Pre-labelling versus direct labelling of anthrax proteins for imaging of matrix metalloproteinases activity using DOTA-GA
由: Xavier, M-AE, et al.
出版: (2019) -
Radiolabeled cCPE peptides for SPECT imaging of claudin-4 overexpression in pancreatic cancer
由: Baguna-Torres, J, et al.
出版: (2020) -
Radiolabelled Bacillus anthracis toxin-based probes for molecular imaging of MMP activity in tumour models
由: Xavier, M, et al.
出版: (2018) -
Dual-isotope imaging reveals inter-individual differences in passive uptake of radiolabelled antibodies in tumours
由: Knight, J, et al.
出版: (2018)