Development of models and methods to assess the efficacy of anti-cancer drugs targeted to the mitochondria
<p><strong>Background:</strong> Malignant transformation of cells is typically characterised by aerobic glycolysis, resulting in supressed mitochondrial function, a state that helps resistance to apoptosis. This characteristic has been widely accepted as a hallmark of cancer and ha...
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| Format: | Thesis |
| Jezik: | English |
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2014
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