E2F1: Cause and consequence of DNA replication stress

In mammalian cells, cell cycle entry occurs in response to the correct stimuli and is promoted by the transcriptional activity of E2F family members. E2F proteins regulate the transcription of S phase cyclins and genes required for DNA replication, DNA repair, and apoptosis. The activity of E2F1, th...

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Bibliographic Details
Main Authors: Fouad, S, Hauton, D, D'Angiolella, V
Format: Journal article
Language:English
Published: Frontiers Media 2021