APC-targeted DNA vaccination against reticulocyte-binding protein homolog 5 induces plasmodium falciparum-specific neutralizing antibodies and t-cell responses

Targeted delivery of antigen to antigen presenting cells (APCs) is an efficient way to induce robust antigen-specific immune responses. Here, we present a novel DNA vaccine that targets the <i>Plasmodium falciparum</i> reticulocyte-binding protein homolog 5 (PfRH5), a lea...

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Bibliographic Details
Main Authors: Bjerkan, L, Visweswaran, GRR, Gudjonsson, A, Labbé, GM, Quinkert, D, Pattinson, DJ, Spång, HCL, Draper, SJ, Bogen, B, Braathen, R
Format: Journal article
Language:English
Published: Frontiers Media 2021