Conformational changes during the gating of a potassium channel revealed by structural mass spectrometry.

Potassium channels are dynamic proteins that undergo large conformational changes to regulate the flow of K(+) ions across the cell membrane. Understanding the gating mechanism of these channels therefore requires methods for probing channel structure in both their open and closed conformations. Rad...

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Main Authors: Gupta, S, Bavro, V, D'Mello, R, Tucker, S, Vénien-Bryan, C, Chance, MR
格式: Journal article
语言:English
出版: 2010