An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1gene

<p style="text-align:justify;"> <b>Background:</b> Multiple sclerosis (MS) is a complex trait in which genes in the MHC class II region exert the single strongest effect on genetic susceptibility. The principal MHC class II haplotype that increases MS risk in individuals...

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Bibliographic Details
Main Authors: Ramagopalan, S, McMahon, R, Dyment, D, Sadovnick, A, Ebers, G, Wittkowski, K
Format: Journal article
Language:English
Published: BioMed Central 2009