l‐Dopa responsiveness is associated with distinctive connectivity patterns in advanced Parkinson's disease

BACKGROUND:Neuronal loss and dopamine depletion alter motor signal processing between cortical motor areas, basal ganglia, and the thalamus, resulting in the motor manifestations of Parkinson's disease. Dopamine replacement therapy can reverse these manifestations with varying degrees of improv...

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Bibliographic Details
Main Authors: Akram, H, Wu, C, Hyam, J, Foltynie, T, Limousin, P, De Vita, E, Yousry, T, Jahanshahi, M, Hariz, M, Behrens, T, Ashburner, J, Zrinzo, L
Format: Journal article
Language:English
Published: Wiley 2017