Molecular detection of localized prostate cancer using quantitative methylation-specific PCR on urinary cells obtained following prostate massage.

PURPOSE: The diagnosis of localized prostate cancer is difficult due to a lack of cancer-specific biomarkers. Many patients require repeat prostate biopsies to diagnose the disease. We investigated whether aberrant promoter hypermethylation in prostatic fluid could reliably detect prostate cancer....

Полное описание

Библиографические подробности
Главные авторы: Rouprêt, M, Hupertan, V, Yates, DR, Catto, J, Rehman, I, Meuth, M, Ricci, S, Lacave, R, Cancel-Tassin, G, de la Taille, A, Rozet, F, Cathelineau, X, Vallancien, G, Hamdy, F, Cussenot, O
Формат: Journal article
Язык:English
Опубликовано: 2007