Quantification of CD4(+) T cell alloreactivity and its control by regulatory T cells using time lapse microscopy and immune synapse detection.

Assays designed to select transplant recipients for immunosuppression withdrawal have met with limited success, perhaps because they measure events downstream of T cell-alloantigen interactions. Using in vitro time lapse microscopy in a mouse transplant model we asked whether transplant outcome woul...

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Bibliographic Details
Main Authors: Juvet, S, Sanderson, S, Hester, J, Wood, K, Bushell, A
Format: Journal article
Language:English
Published: Wiley 2015