Investigating molecular vulnerabilities in TP53-mutant transformed myeloproliferative neoplasms
<p>Myeloproliferative neoplasms (MPN) are chronic haematological disorders characterised by activating mutations within the JAK-STAT signalling pathway. MPN are a heterogenous spectrum of stem cell-derived neoplasm defined by excess clonal proliferation of mature myeloid entities. Clinical com...
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| Format: | Thesis |
| Language: | English |
| Published: |
2024
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