Determination of pore-lining residues in the hepatitis C virus p7 protein.

The p7 protein from hepatitis C virus is critical for the assembly and secretion of infectious virus, making it an attractive drug target. It is thought to be a viroporin with a demonstrated ion channel activity when reconstituted into planar lipid bilayers. Electron microscopy experiments suggest t...

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Bibliografski detalji
Glavni autori: Chew, C, Vijayan, R, Chang, J, Zitzmann, N, Biggin, P
Format: Journal article
Jezik:English
Izdano: Cell Press 2009