Crystal structure of rhodocytin, a ligand for the platelet-activating receptor CLEC-2.

Binding of the snake venom protein rhodocytin to CLEC-2, a receptor on the surface of human platelets, initiates a signaling cascade leading to platelet activation and aggregation. We have previously solved the structure of CLEC-2. The 2.4 A resolution crystal structure of rhodocytin presented here...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Watson, A, Eble, J, O'Callaghan, C
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2008