PRMT5 controls the innate immune response

<p>Protein arginine methyltransferase 5 (PRMT5) is a symmetric di-methyltransferase frequently overexpressed in various cancers, including colorectal cancer. It is known that PRMT5-mediated methylation of E2 promoter binding factor 1 (E2F1) not only supports cancer cell growth but also influen...

Full description

Bibliographic Details
Main Author: Zhang, C
Other Authors: La Thangue, N
Format: Thesis
Language:English
Published: 2024