Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations.
In the search for effective vaccines against intracellular pathogens such as HIV, tuberculosis and malaria, recombinant viral vectors are increasingly being used to boost previously primed T cell responses. Published data have shown prime-boost vaccination with BCG-MVA85A (modified vaccinia virus An...
Autori principali: | Beveridge, N, Price, D, Casazza, J, Pathan, A, Sander, C, Asher, T, Ambrozak, DR, Precopio, M, Scheinberg, P, Alder, N, Roederer, M, Koup, R, Douek, D, Hill, A, Mcshane, H |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2007
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