Cytokine expression and networks in rheumatoid arthritis: rationale for anti-TNF alpha antibody therapy and its mechanism of action.
The cloning of cytokine cDNAs has permitted the analysis of cytokine expression in diseased sites such as rheumatoid joints. A very wide range of cytokines were detected, mostly with proinflammatory activities. From the analysis of cytokine regulation in rheumatoid joint cell cultures using neutrali...
Huvudupphovsmän: | Feldmann, M, Brennan, F, Williams, R, Elliott, M, Maini, R |
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Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
1995
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