Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

Diffuse intrinsic pontine gliomas (DIPGs) are highly infiltrative malignant glial neoplasms of the ventral pons that, due to their location within the brain, are unsuitable for surgical resection and consequently have a universally dismal clinical outcome. The median survival time is 9-12 months, wi...

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Bibliographic Details
Main Authors: Taylor, K, Mackay, A, Truffaux, N, Butterfield, Y, Morozova, O, Philippe, C, Castel, D, Grasso, C, Vinci, M, Carvalho, D, Carcaboso, A, de Torres, C, Cruz, O, Mora, J, Entz-Werle, N, Ingram, W, Monje, M, Hargrave, D, Bullock, A, Puget, S, Yip, S, Jones, C, Grill, J
Format: Journal article
Language:English
Published: Nature Publishing Group 2014