Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

Diffuse intrinsic pontine gliomas (DIPGs) are highly infiltrative malignant glial neoplasms of the ventral pons that, due to their location within the brain, are unsuitable for surgical resection and consequently have a universally dismal clinical outcome. The median survival time is 9-12 months, wi...

詳細記述

書誌詳細
主要な著者: Taylor, K, Mackay, A, Truffaux, N, Butterfield, Y, Morozova, O, Philippe, C, Castel, D, Grasso, C, Vinci, M, Carvalho, D, Carcaboso, A, de Torres, C, Cruz, O, Mora, J, Entz-Werle, N, Ingram, W, Monje, M, Hargrave, D, Bullock, A, Puget, S, Yip, S, Jones, C, Grill, J
フォーマット: Journal article
言語:English
出版事項: Nature Publishing Group 2014