Homocysteine modification of HLA antigens and its immunological consequences.

Homocysteine-treated cells can be specifically lysed by cytotoxic T lymphocytes (CTL) identifiable in patients with ankylosing spondylitis and reactive arthritis. Sensitization of target cells involves disulfide bonding and the interaction between homocysteine and HLA antigens occurs in a pre-Golgi...

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Bibliographic Details
Main Authors: Gao, X, Wordsworth, P, Mcmichael, A, Kyaw, M, Seifert, M, Rees, D, Dougan, G
Format: Journal article
Language:English
Published: 1996