Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: Characterisation and selection of candidates for pre-clinical development

Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: Characterisation and selection of candidates for pre-clinical development

<p style="text-align:justify;">The interleukin (IL)-13 pathway and its associated transcription factor, signal transducer and activator of transcription 6 (STAT6), have been clearly implicated in the pathogenesis of bronchial asthma. We have developed a system to effectively screen t...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Healey, G, Zinnen, S, Lockridge, J, Richard, I, Evans, N, Walker, W
Μορφή:	Journal article
Έκδοση:	Library Publishing Media 2010

Παρόμοια τεκμήρια

Development of pre-clinical models for evaluating the therapeutic potential of candidate siRNA targeting STAT6.
ανά: Gareth D Healey, κ.ά.
Έκδοση: (2014-01-01)

Small interfering RNA : new research /
ανά: Yamada, Kaito, κ.ά.
Έκδοση: (2009)

Inhibition of Gene Expression by Small Interfering RNA on // Signaling Pathway in Human Nasopharyngeal Carcinoma
ανά: Liang Zhong Yao MM, κ.ά.
Έκδοση: (2020-04-01)

Small interfering RNA against BCR-ABL transcripts sensitize mutated T315I cells to nilotinib
ανά: Michael Koldehoff, κ.ά.
Έκδοση: (2010-03-01)

Tumor-penetrating delivery of small interfering RNA therapeutics
ανά: Ren, Yin, Ph. D. Massachusetts Institute of Technology
Έκδοση: (2012)

Small interfering RNA inhibition of Andes virus replication.
ανά: Cheng-Feng Chiang, κ.ά.
Έκδοση: (2014-01-01)

Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy
ανά: Lang Lin, κ.ά.
Έκδοση: (2023-03-01)

Small interfering RNA against transcription factor STAT6 leads to increased cholesterol synthesis in lung cancer cell lines.
ανά: Richa Dubey, κ.ά.
Έκδοση: (2011-01-01)

An Atelocollagen Coating for Efficient Local Gene Silencing by Using Small Interfering RNA
ανά: Olivia Koenig, κ.ά.
Έκδοση: (2017-03-01)

Small interfering RNA: potential in real-world clinical practice
ανά: A. S. Motrinchuk, κ.ά.
Έκδοση: (2024-04-01)

Cholesterol Conjugates of Small Interfering RNA: Linkers and Patterns of Modification
ανά: Ivan V. Chernikov, κ.ά.
Έκδοση: (2024-02-01)

Phenotypic Alteration of BMDM In Vitro Using Small Interfering RNA
ανά: Noreen Halimani, κ.ά.
Έκδοση: (2022-08-01)

Potential Application of Small Interfering RNA in Gastro-Intestinal Tumors
ανά: Pasquale Losurdo, κ.ά.
Έκδοση: (2022-10-01)

Small Interfering RNA for Gliomas Treatment: Overcoming Hurdles in Delivery
ανά: Xin-Qi Teng, κ.ά.
Έκδοση: (2022-07-01)

Small Interfering RNA in Colorectal Cancer Liver Metastasis Therapy
ανά: Junlin Xie MM, κ.ά.
Έκδοση: (2022-07-01)

Small Interfering RNA Therapeutics in Hypertension: A Viewpoint on Vasopressor and Vasopressor‐Sparing Strategies for Counteracting Blood Pressure Lowering by Angiotensinogen–Targeting Small Interfering RNA
ανά: Priyanga Ranasinghe, κ.ά.
Έκδοση: (2022-10-01)

Small Interfering RNA Efficiently Suppresses Adhesion Molecule Expression on Pulmonary Microvascular Endothelium
ανά: Tobias Walker, κ.ά.
Έκδοση: (2011-01-01)

Signal transducers and activators of transcription (STATs) : activation and biology /
ανά: Sehgal, Pravinkumar B., κ.ά.
Έκδοση: (2003)

Porous silicon nanotube bundles as nanocarriers for small interfering RNA delivery
ανά: Nguyen T. Le, κ.ά.
Έκδοση: (2024-08-01)

Delivery of Thrombospondin-2 Small Interfering RNA for Suppression of Intimal Hyperplasia
ανά: Jennifer R. Li, κ.ά.
Έκδοση: (2021-01-01)

Secondary Small Interfering RNA-Based Silencing Tools in Plants: An Update
ανά: Alberto Carbonell
Έκδοση: (2019-05-01)

Inclisiran—Safety and Effectiveness of Small Interfering RNA in Inhibition of PCSK-9
ανά: Łukasz Wołowiec, κ.ά.
Έκδοση: (2023-01-01)

Delivery of therapeutic small interfering RNA: The current patent-based landscape
ανά: Yu Chen, κ.ά.
Έκδοση: (2022-09-01)

Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy
ανά: Miele E, κ.ά.
Έκδοση: (2012-07-01)

Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis
ανά: Mitsutoshi Kurosaka, κ.ά.
Έκδοση: (2021-05-01)

Pre-Clinical and Clinical Applications of Small Interfering RNAs (siRNA) and Co-Delivery Systems for Pancreatic Cancer Therapy
ανά: Sepideh Mirzaei, κ.ά.
Έκδοση: (2021-11-01)

Colored petri net modeling of small interfering RNA-mediated messenger RNA degradation
ανά: Niloofar Nickaeen, κ.ά.
Έκδοση: (2016-01-01)

Small interfering RNA (siRNA): a hope for the loss-of-function studies in anesthesiology?
ανά: Yun Hong Kim
Έκδοση: (2010-12-01)

A small interfering RNA (siRNA) database for SARS-CoV-2
ανά: Inácio Gomes Medeiros, κ.ά.
Έκδοση: (2021-04-01)

Virus-Derived Small Interfering RNAs Affect the Accumulations of Viral and Host Transcripts in Maize
ανά: Zihao Xia, κ.ά.
Έκδοση: (2018-11-01)

The Roles of Signal Transducer and Activator of Transcription 3 in Tumor Metastasis
ανά: Lei GONG, κ.ά.
Έκδοση: (2010-10-01)

Signal transducers and activators of transcription 6 (Stat6) variants in childhood and adult asthma
ανά: Michiko Suzuki, κ.ά.
Έκδοση: (2004-01-01)

Clinical application of small interfering RNA in cardiovascular diseases: A bibliometric analysis
ανά: Jialian Lv, κ.ά.
Έκδοση: (2025-03-01)

siRNAEfficacyDB: An experimentally supported small interfering RNA efficacy database
ανά: Yang Zhang, κ.ά.
Έκδοση: (2024-12-01)

The potential of synthetic small interfering RNA-based antiviral drugs for influenza treatment
ανά: E. A. Pashkov, κ.ά.
Έκδοση: (2020-09-01)

An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons
ανά: Porreca Frank, κ.ά.
Έκδοση: (2005-09-01)

Inhibitory effect of small interfering RNA on dengue virus replication in mosquito cells
ανά: Li Lei, κ.ά.
Έκδοση: (2010-10-01)

Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra.
ανά: Alison L McCormack, κ.ά.
Έκδοση: (2010-01-01)

Small interfering RNA-producing loci in the ancient parasitic eukaryote <it>Trypanosoma brucei</it>
ανά: Tschudi Christian, κ.ά.
Έκδοση: (2012-08-01)

Correction: Functional Specialization of the Small Interfering RNA Pathway in Response to Virus Infection.
ανά: Joao Trindade Marques, κ.ά.
Έκδοση: (2013-10-01)