Broad HIV-1 inhibition in vitro by vaccine-elicited CD8+ T cells in African adults

We are developing a pan-clade HIV-1 T-cell vaccine HIVconsv, which could complement Env vaccines for prophylaxis and be a key to HIV cure. Our strategy focuses vaccine-elicited effector T-cells on functionally and structurally conserved regions (not full-length proteins and not only epitopes) of the...

Full description

Bibliographic Details
Main Authors: Mutua, G, Farah, B, Langat, R, Indangasi, J, Ogola, S, Onsembe, B, Kopycinski, J, Hayes, P, Borthwick, N, Ashraf, A, Dally, L, Barin, B, Tillander, A, Gilmour, J, De Bont, J, Crook, A, Hannaman, D, Cox, J, Anzala, O, Fast, P, Reilly, M, Chinyenze, K, Jaoko, W, Hanke, T, HIV-CORE 004 study group
Format: Journal article
Language:English
Published: Elsevier 2017