Residue-selective protein C-formylation via sequential difluoroalkylation-hydrolysis

The carbonyl group is now a widely useful, nonproteinogenic functional group in chemical biology, yet methods for its generation in proteins have relied upon either cotranslational incorporation of unnatural amino acids bearing carbonyls or oxidative conversion (chemical or enzymatic) of existing na...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Imiołek, M, Isenegger, PG, Ng, W-L, Khan, A, Gouverneur, V, Davis, BG
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: American Chemical Society 2021