Sex-differential impact of human cytomegalovirus infection on in vitro reactivity to toll-like receptor 2, 4 and 7/8 stimulation in Gambian infants

Human cytomegalovirus (HCMV) infection rates approach 100% by the first year of life in low-income countries. It is not known if this drives changes to innate immunity in early life and thereby altered immune reactivity to infections and vaccines. Given the panoply of sex differences in immunity, it...

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Detalhes bibliográficos
Principais autores: Cox, M, Adetifa, JU, Noho-Konteh, F, Sanyang, LC, Drammeh, A, Plebanski, M, Whittle, HC, Rowland-Jones, SL, Robertson, I, Flanagan, KL
Formato: Journal article
Idioma:English
Publicado em: MDPI 2020