Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases.

While the oxygen-dependent reversal of lysine N(ɛ)-methylation is well established, the existence of bona fide N(ω)-methylarginine demethylases (RDMs) is controversial. Lysine demethylation, as catalysed by two families of lysine demethylases (the flavin-dependent KDM1 enzymes and the 2-oxoglutarate...

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Bibliographic Details
Main Authors: Walport, L, Hopkinson, R, Chowdhury, R, Schiller, R, Ge, W, Kawamura, A, Schofield, C
Format: Journal article
Language:English
Published: Nature Publishing Group 2016